Oxygenation Mapping

HyperMed’s OxyVu technology assesses the viability of the superficial dermis by measuring the functional capacity of tissue to process oxygen:

Tissues have optical signatures from chromophores that reflect their chemical characteristics.

Two major chromophores of physiological relevance:

• Oxyhemoglobin (OxyHb)

• Deoxyhemoglobin (DeoxyHb)

OxyVu efficiently measures OxyHb and DeoxyHb across 1 million pixels in about 20 seconds.

This data is used to create a map of local oxygen delivery and extraction within the tissue microvasculature.

Measures Microvascular Perfusion

• Quantitative and qualitative physiologic assessment of tissue viability
• Research revealed it was not subject to distortion caused by vessel calcification

Published Clinical Studies Showed:

• 92% in vivo correlation to a spectrometer
• 90% PPV in predicting wound healing
• 87% PPV in predicting revascularization success
• 88% PPV in amputation planning

CLI: Limb Preservation

• Clinical studies have shown that OxyVu may be used to help identify patients at risk for developing critical
limb ischemia missed by other modalities
– 40% of diabetic claudicants progress to CLI due to calcification of
vessels and pain-masking caused by neuropathy

Rapid and Non-contact

• Real-time assessment of regional oxygenation provided in a
20-second scan
• Non-contact system eliminates the potential for cross-contamination
• Archiving capability permits historical analysis across multiple patient
visits for progress tracking