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Case Study: Diabetic Ulcer Healing

The color bar can be used to quickly identify different regions of tissue oxygenation that then can be quantified by using the HyperVu software. HT-oxy levels are related to color changes (low to high, yellow to purple) – HT-deoxy levels are related to brightness (low to high, pale to brilliant).

This 43 year old Indian female with type I diabetes with an ulcer of the sub hallux interphalangeal joint of the right foot was followed for 1 year. She also had diagnoses of hyperlipidemia, hypertension, hypothyroidism and peripheral neuropathy. She had been admitted two months previously for acute cellulitis of the right foot and diagnosed with osteomyelitis of the right hallux distal and proximal phallanx by MRI and bone scan. She had been treated with IV ertapenem for 6 weeks followed by oral antibiotics. The ulcer can be seen to be largely healed one month later.

A positive HTcOM Healing Index around the ulcer at the first visit was consistent with healing wounds and would support continued conservative therapy. In other subjects, a negative HTcOM Healing Index was associated with non-healing and would support a more aggressive approach including offloading, hyperbaric therapy, or angiography and revascularization.

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